Bundesautobahnen19 (A19) and 20 (A20) meet near Rostock. The A19 brings truckers to Berlin and other settlements to the south; while the A20 leads truckers to the west, with Bundesautobahn 1 taking over after a short distance. Hamburg is the next city to the west.
With the release of Scandinavia DLC, seaport facilities are added north of Rostock, making the city become one of the most important access points to the new destinations. If a trucker does not have the Going East DLC enabled, Rostock is, in fact, the easternmost access point towards Scandinavia.